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A significant association was observed that high NLR and PLR predict poor overall survival and disease-free survival. Conclusions NLR and PLR can be used as available biomarkers in prognostic survival and formulation of treatment strategy of multiple cancers.Background Anemia and vitamin D deficiency are two important public health issues that may accompany many acute and chronic diseases. Several studies conducted in recent years have suggested that vitamin D deficiency is associated with anemia in healthy and patient populations. The