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uction strategies and treatment. We examined whether duration of electronic cigarette (e-cigarette) use could be associated with smoking reduction or cessation attempt. 5,409 current smokers at baseline enrolled in the French CONSTANCES cohort in 2015 or 2016 were included. Duration of e-cigarette use was categorized as follows never; former user for more than one year; former user for less than one year; new user for less than one year; return to use for less than one year; regular use for one to two years; regular use for more than two y