https://www.selleckchem.com/pr....oducts/epoxomicin-bu
The role of the innate immune system in functional gastrointestinal pain disorders is unclear. We investigated the role of β-defensin-2 and gut permeability in childhood irritable bowel syndrome (IBS) and functional abdominal pain (FAP) symptom generation. Fecal β-defensin-2 (and in a subset, gut permeability) was measured in children with IBS (n= 116), FAP (n= 33), and healthy control (HC) children (n= 72). IBS and FAP patients were recruited from tertiary and primary care, and HCs were recruited from primary care. β-defens