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What is the Best Treatment For ADHD in Adults? The majority of people with ADHD will benefit from a combination treatment. The treatments typically are multimodal and may include therapy, medication and lifestyle changes. Stimulants are among the most commonly used medications for ADHD. Finding the right dose and balancing the side effects can be a challenge. Atomoxetine is a FDA-approved non-stimulant that is not a stimulant and does not carry the potential to abuse that stimulants do. It is a pill that can be taken orally. Medication Adu