https://www.selleckchem.com/pr....oducts/dorsomorphin-
In stage I, 14 (24.1%), patients died during 28days, and the expression of PD-1 in Tregs (OR1.037;95%CI1.003-1.071) and SOFA scores(OR1.262;95%CI1.046-1.524) were independent risk factors for 28-day mortality. The ability of Tregs PD-1 in predicting 28-day mortality was validated in stage II (AUC=0.792). PD-1 overexpression in Tregs was associated with poor outcomes, and PD-1 in Tregs is considered to be a valuable tool for the prediction of prognosis in septic patients using sepsis-3.0 criteria. PD-1 overexpression in Tregs w