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The goal of this research is to measure the connection between serum qHBsAg levels and viral replication and stage of liver fibrosis in treatment-naive CHB clients also to determine the part of qHBsAg levels in predicting when liver biopsy is essential. Information and methods 967 patients had been within the research. As a result of refusal of liver biopsy the study ended up being conducted on 123 clients. The connection between qHBsAg amounts with HBV DNA, a-fetoprotein, fi