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We additional program that streptonigrin treated cells display compacted DNA foci into the nucleus that co-localize with Heterochromatin Protein 1 alpha (HP1α), and exhibit an increase in total quantities of the heterochromatin mark, H3K9me3. Interestingly, we found that streptonigrin promotes heterochromatin at a concentration as little as one nanomolar, and at this focus there were no noticeable results on cell expansion or viability. Finally, in line with a previous report, we fou
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