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Patients were randomly assigned to endure RDN through the adventitia for the renal artery plus adrenalectomy (RDN group, n = 3 or adrenalectomy alone (control group, n = 3 and were followed up for one year. The main effectiveness end-point ended up being the change in 24-hours mean ambulatory systolic blood circulation pressure (SBP) from baseline to one year. In the 12-month follow-up, the mean reduced total of 24-hours average SBP and office SBP in the RDN group was 20.7 ± 15.2 and 37.1 ± 26.0 mm Hg, r