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Moreover, a comparison of CD4+CD52high T cells and CD4+CD52low T cells showed that many T2DM-related genes were aberrantly expressed. Overall, CD52 may functioned as an important potential target for obesity with T2DM via TGF-β/Smad3 axis. To evaluate the efficacy of poly ADP ribose polymerase (PARP) inhibitors (PARPis) in breast and ovarian cancer with (BReast CAncer susceptibility gene) mutation (BRCAm). We conducted a meta-analysis of randomized controlled, phase II or III trials by searching of electronic databases from inception to S