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In megakaryopoiesis, GATA1s causes a differentiation wait at a certain phase, with accumulation of immature, kit-expressing CD41hi megakaryocytic cells. In this specific megakaryocytic compartment, you will find increased numbers of GATA1s cells in S-phase of cellular period and paid off range apoptotic cells when compared with GATA1 cells in identical mobile area. Additionally there is a delay in maturation of these immature GATA1s megakaryocytic lineage cells when compared with GATA1 cells