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Mid-career nurse scientists are at risk of burnout and departure from research-focused roles due to a myriad of reasons, including a nationwide faculty shortage, vacant administrative roles, and the challenging extramural funding environment. Retention and success of mid-career scientists in any health-related discipline is essential to maintain educational and research endeavors that are important for public health and well-being. This commentary provides an account of recent efforts to address these issues, from the perspective of a