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07 (95% confidence interval, CI 1.03-1.1; 0.001]. After stratification in individuals 65 years ( = 339) and ≥65 years ( = 342), a prognostic effect of the PLR on cardiovascular mortality was solely observed in elderly patients ≥65 years [adj. HR per 1 SD of 1.04 (95% CI 1.00-1.08); = 0.039], but not in their younger counterparts 65 years [adj. HR per 1 SD of 0.97 (95% CI 0.83-1.14); = 0.901]. The present investigation highlights a strong and independent age-specific association of the PLR with cardiovascular mortality in