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Many solitary nucleotide polymorphisms happen identified by genome-wide relationship studies and were discovered to be associated with PE; nonetheless, few research reports have used whole-exome sequencing (WES) to recognize PE alternatives. METHODS Five patients with extreme early-onset preeclampsia (EOPE) were recruited, and WES had been done for each client. Sanger sequencing was used to verify the potential causative genetic variation. OUTCOMES After a stringent bioinformatics
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