https://www.selleckchem.com/pr....oducts/merbarone.htm
To investigate the association of several single-nucleotide polymorphisms (SNPs) within methylenetetrahydrofolate reductase (MTHFR) gene, and additional gene-environment interaction with ischemic stroke (IS) risk. Testing for Hardy-Weinberg equilibrium in controls was conducted using SNPstats (online software http//bioinfo.iconcologia.net/SNPstats). Generalized multifactor dimensionality reduction (GMDR) was used to screen the best interaction combination among four SNPs within MTHFR gene and smoking or alcohol drinking. The frequency