https://berzosertibinhibitor.c....om/increasing-nonfou
MTT assays, circulation cytometric analysis, Western blotting and immunohistochemistry identified that ZJQ-24 efficiently suppressed hepatocellular carcinoma mobile expansion via G2/M stage arrest and caspase-dependent apoptosis but had no cytotoxic on normal cells. Additionally, ZJQ-24 somewhat blocked AKT/mTOR signaling by down-regulation of mTORC1 molecules, including phospho-p70S6K (Thr389) and phospho-4EBP-1 (Ser65, Thr37/46