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ADHD Medication For Adults - What is the Most Effective ADHD Medication For Adults? Stimulant medication is the mainstay of ADHD treatment however they aren't effective for all people. Nonstimulant drugs and antidepressants may help. Adults who suffer from ADHD can be patches, pills or liquids. They boost concentration and reduce the impulsive behavior. Doctors often prescribe them when stimulants fail