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ADHD Medications For Adults and Teenagers If a person's ADHD medication starts to work properly, they should notice that they are able to concentrate for longer durations. They may also be capable of falling asleep more easily. are the most frequently prescribed stimulants for ADHD. They can either be immediate-release or long acting. Long-acting formulations prevent "crash" effects that can occur when stimulant medications wear off. Methylphenidate Methylphenidate stimulates the c