https://www.selleckchem.com/pr....oducts/nsc-23766.htm
Proteins that recognize the epigenetic modifications function as mediators to interpret the epigenetic codes. Hypoxia response and metabolic rewiring are two major events during cancer progression. However, it's still unclear whether and how epigenetic regulator integrates hypoxia response and metabolism together. We data mined the clinical association of 33 histone Kac reader proteins with liver cancer and that AF9 is upregulated in cancer and correlates with tumor stage and poor prognosis. Conditional deletion of Af9 in mouse liver
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