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0 mm. The average volume of the sampled tissue is about 0.35 mm . We designed a MABC robot and proposed a control framework which enables planar and 3D spatial locomotion and biopsy sampling. The untethered MABC robot can be remotely controlled to achieve accurate sampling in multiple directions without internal power sources, paving the way towards precision sampling techniques for GI diseases in clinical procedures. The untethered MABC robot can be remotely controlled to achieve accurate sampling in multiple directions without internal