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In the cause-specific hazard model, the multivariable HRs (95%CI) for the association of hs-CRP of 1-3 mg/L group and hs-CRP3 mg/L with PLC were 1.06(0.81 ~ 1.4, 1.50(1.14 ~ 1.99). Similar results were also observed in the sub-distribution hazard function model with corresponding multivariate HRs (95%CI) of 1.05(0.80 ~ 1.4, 1.49(1.13 ~ 1.98) in hs-CRP of 1-3 mg/L group and hs-CRP3 mg/L group, respectively. This prospective study found a significant association of higher levels of hs-CRP with new-onset PLC. The main clinical imp