https://www.selleckchem.com/pr....oducts/SB-203580.htm
7-85.5%), a specificity of 84.6% (95% confidence interval 76.2%-90.9%), and accuracy of 81.2% (95% confidence interval 74.4%-86.9%) in predicting loss of function PTEN mutation. PTEN abnormality by complementary interpretation of both assays was present in 91.9% of endometrial endometrioid carcinoma, grade 1, and significantly higher in endometrial endometrioid carcinomas of all grades compared with endometrial serous carcinoma (80.0% vs. 19.4%, P less then 0.0001). PTEN abnormalities are common across all molecular subtypes of endome
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