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Purpose Health-related quality of life (HRQOL) reflects a perceived sense of physical and mental well-being over time, encompassing both physical health and psychosocial health. Although these two health concepts have been often examined as a whole, few studies have explored the possibility of mixed profiles. We designed this study to identify Chinese adolescents' HRQOL profiles and their associations with happiness, physical activity, and fitness. Method 544 high-school students completed validated Chinese-version questionnaires assess
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