https://www.selleckchem.com/
These data suggest AKR1B8 deficiency leads to abnormalities of intestinal epithelial barrier and immunity in colon.Hemophilia A (HA), an X-linked recessive congenital bleeding disorder, affects 80%-85% of patients with hemophilia. Nearly half of severe cases of hemophilia are caused by a 0.6-Mb genomic inversion (Inv22) that disrupts F8. Although viral-based gene therapy has shown therapeutic effects for hemophilia B (H, this promising approach is not applicable for HA at the present stage; this limitation is mainly due to the large size of F8 cDNA, which
Like
Comment
Share
