https://www.selleckchem.com/pr....oducts/xl413-bms-863
In patient-derived primary AML cells, vitamin C only restored TET2 activity when SLC2A3 was expressed. CONCLUSION SLC2A3 could be used as a potential biomarker to predict the effect of vitamin C treatment in AML.BACKGROUND Cardiotoxicity is the most significant adverse event associated with trastuzumab (T), the main component of HER2-positive breast cancer (BC) treatment. Less is known about the cardiotoxicity of dual HER2 blockade with T plus lapatinib (L), although this regimen is used in the metastatic setting. METHODS This
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