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Patients with Trisomy 21 had a shorter duration of mechanical ventilation after the change in practice. Conclusion The findings from this study affirm the importance of the nurses' role in managing prescribed analgesia and sedation supported by best available evidence. A continued education and awareness focus on analgesia and sedation management in the pursuit of best patient care is imperative.Objectives This meta-analysis examined effects of health coaching on physical activities, dietary behaviors, health responsibility, stress manag