https://www.selleckchem.com/pr....oducts/s-gsk1349572.
In this study, mutations in the tripanothion reductase of isolated from Iran was investigated using sequencing and simulation of the enzyme by the molecular dynamic method. Fifteen susceptible and 15 clinical resistant specimens were collected from skin lesions from different regions of Iran in 2017. After DNA extraction, trypanothione reductase ( or ), gene fragment was amplified using PCR and sequencing methods. In the case of structural mutations, the components were simulated by molecular dynamics using the GROMACS software. So
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