https://cd177signaling.com/the....-partnership-between
When GSK-3 is not phosphorylated by AKT or any other kinases at certain negative-regulatory residues, it can alter the game of many proteins by phosphorylation, a few of these proteins advertise while other individuals inhibit cell expansion. This is certainly the main conundrum regarding GSK-3. The main motif for this review could be the capability of GSK-3 to serve as either a tumor suppressor or a tumor promoter in cancer tumors which is most likely due to its diverse necessary protein subs
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