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The resulting RS was significantly higher in the group of deceased adults compared to elderly adults [p = 0.00348, area under the receiver operating characteristic curve (AUC ROC = 0.68)]. In particular, presence of HLA-A*0101 allele was associated with high risk, while HLA-A*0201 and HLA-A*0301 mainly contributed to low risk. The analysis of patients with homozygosity strongly highlighted these results homozygosity by HLA-A*0101 accompanied early deaths, while only one HLA-A*0201 homozygote died before 60 years of age. Application of th