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02), insulin (p = .02), NEFA concentrations (p = .001) and HOMA-IR (p less then .01) despite reduced steps (p less then .01) and increased sedentary time (p less then .01). Abdominal adipose tissue (AT) samples, obtained after baseline, SR and exercise, did not differ in lipolytic capacity following SR. Fatty acid synthase protein content tended to increase following SR (p = .07), but not following exercise. In a free-living setting, SR adversely affected circulating NEFAs, fuel oxidation and peak glucose response but did not directly af