https://www.selleckchem.com/pr....oducts/guanosine.htm
Finally, the future outlook and challenges associated with the large-scale fabrication of MOF-based composites for practical applications are discussed.The development of efficacious NNRTIs for AIDS therapy commonly encountered the rapid generation of drug-resistant mutations, which becomes a major impediment to effective anti-HIV treatment. Using a structure-based bioisosterism strategy, a series of piperidine-substituted thiophene[2,3-d]pyrimidine derivatives were designed and synthesized. Compound 9a yielded the greatest potency, e
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