https://www.selleckchem.com/pr....oducts/ro5126766-ch5
Although sodium increases the risk of coronary artery disease and hypertension, whether sodium also impacts other cardiovascular disease (CVD) and its risk factors is less clear. We examined the causal role of urinary sodium in these CVDs and risk factors using Mendelian randomization. We identified strong, independent single nucleotide polymorphisms (SNPs) of urinary sodium from the most up to date genome wide association studies (GWAS) (n=446,237) and applied them to GWAS of stroke and its subtypes (40,585 cases and 406,11
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