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Receiver operating characteristic (ROC) analysis showed that serum GPI could screen KOA patients from controls. Collectively, elevated serum GPI concentration contributed to the progression of KOA, and targeting GPI may be useful for the therapy of KOA. Collectively, elevated serum GPI concentration contributed to the progression of KOA, and targeting GPI may be useful for the therapy of KOA. South Korea is the only Organisation for Economic Co-operation and Development (OECD) country with a high incidence of tuberculosis (T. Healthcar