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The percentage of indenting cells from invasive (26.2 ± 2.4%) and non-invasive (4.8 ± 0.5%) SCC samples differed significantly (p 12% and less then 5%. The mechanical invasiveness directly agrees with the SCC cell-differentiation state, where over 3.3-fold more (p less then 0.0001) cells from moderately differentiated samples indent the gels as compared to well-differentiated cell samples. In BCCs, less then 20% of cells typically indented, and a highly migratory, desmoplastic sample was identified with 46%. By providing rapid, q
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