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0 (MCF-7) are obtained. These selectivity indices are significantly higher than those obtained for the reference drugs cisplatin or auranofin. Acute left atrial ridge (LAR) lesions have been observed following atrial fibrillation (AF) ablation. However, LAR lesions had not yet been quantitatively evaluated and their influence on procedure combining cryoballoon (C ablation with left atrial appendage closure (LAAC) remained to be explored. The profile of LAR lesions was measured by transesophageal echocardiography (TEE) in 117 consecutive