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06). After that, TE group maintained this tendency, reaching the lowest CFT value at 36 months, whereas PRN group showed an increased in CFT values (PRN -104 [-807.7 to +297] μm and TE -103 [-575 to +244], μm p=0.63). Patients treated with TE regimen received a significantly higher number of injections (PRN 16.3±7.6 vs TE 23.9 ±9.4, p less then 0.01). CONCLUSION Our results demonstrated a trend towards for TE to achieve higher marks in BCVA, peaking at 12 months, and lower CFT thickness at the end of three years.