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Taken together , the outcome of the study suggest that 1,25(OH)2D insufficiency accelerates age-related bone tissue loss by increasing oxidative tension and DNA harm, inducing bone cellular senescence and SASP, and afterwards inhibiting osteoblastic bone formation while revitalizing osteoclastic bone resorption. AJTR Copyright © 2020.Chronic obstructive pulmonary disease (COPD) is a devastating and common breathing infection chara