https://www.selleckchem.com/pr....oducts/gw806742x.htm
This work provides evidence on how the QS hierarchy can change from being strictly LasR-dependent to a LasR-independent RhlR-based hierarchy under phosphate limitation even in the PAO1 type strain.IMPORTANCEPseudomonas aeruginosa is an important pathogen considered a priority for the development of new therapeutic strategies. An important approach to fight its infections relies on blocking quorum sensing. The Las system is the main regulator of the quorum sensing response, so many research efforts aim to block this system in order to
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