https://www.selleckchem.com/pr....oducts/ugt8-in-1.htm
The prediction studies indicated that these compounds have suitable properties to be a drug candidate. mRNA expression studies showed that the derivatives can downregulate the proteins responsible for inflammasome activation and same was reflected in ELISA when the concentration of released cytokine was evaluated. Based on the above results, phenylpropanoic acid derivatives have potential to be developed as specific NLRP3-inflammasome inhibitors.In injury and disease, microglia and astrocytes - two major non-neuronal cell types in the
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