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sNfL may be a potential biomarker reflecting the disease activity in patients with CIDP. sNfL may be a potential biomarker reflecting the disease activity in patients with CIDP.The mandible of vertebrates serves as insertion area for masticatory muscles that originate on the skull, and its functional properties are subject to selective forces related to trophic ecology. The efficiency of masticatory muscles can be measured as mechanical advantage on the mandible, which, in turn, has the property of correlating with bite force and shape