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The caffeine content of coffee also varies widely, depending both on the beans is without question how the coffee is brewed. Coffee generally contains between 60mg and 150mg caffeine per cup. Large sizes (16 oz. or more) could well exceed 200mg of pure caffeine. The higher caffeine content of coffee presents some health issues for heavy coffee customers. This healthful beverage also increases the noradrenaline in your system. This is beneficial since your noradrenaline will be the neurotransmitter that's the responsible for the activation of brown fats in shape.