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This is certainly a potential, observational cohort study. The venue for this study is Gaborone, Botswana, a resource-limited environment with high rates of perinatal exposure to HIV and minimal neurocognitive evaluation tools and expertise. We seek to validate the PennCNB in this environment by culturally adjusting after which administering the adapted type of battery pack to 200 HIV-infected, 200 HIV-exposed uninfected and 24ssessments that may be implemented in resource-lim