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Extensive experiments are performed to qualitatively and quantitatively evaluate the effectiveness of our proposed method. In the meanwhile, it outperforms state-of-the-art methods on three different nuclei segmentation datasets.A holistic multitask regression approach was implemented to tackle the limitations of clinical image analysis. Standard practice requires identifying multiple anatomic structures in multiple planes from multiple anatomic regions using multiple modalities. The proposed novel holistic multitask regression network (H
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