https://www.selleckchem.com/pr....oducts/pf-06650833.h
05). Compared with CON group, the Iba1 protein expression and the number of microglia in prefrontal cortex of T1DM group increased significantly (P less then 0.05). In addition, the mRNA levels of several DAM markers in prefrontal cortex of T1DM group were increased significantly (P less then 0.05). These results suggest that the microglia are activated and transformed to DAM type in the prefrontal cortex of T1DM mice.Astrocytes are a heterogenous group of macroglia present in all regions of the brain and play critical roles in many