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The paper is devoted to investigating the quasi-synchronization issue of fractional-order multi-layer networks with mismatched parameters under delay-dependent impulsive feedback control. It is worth highlighting that fractional-order multi-layer networks with mismatched parameters, as the extension model for single-layer or two-layer ones, are constructed in this paper. Simultaneously, the intra-layer and inter-layer couplings are taken into consideration, which is more general and rarely considered in discussions of network synchronization. An extended fr