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How to Choose the Best ADHD Medication for Adults With Anxiety and Depression When a person has both ADHD and depression or anxiety, treating one condition often improves the other. Mental health professionals often prescribe antidepressants or a stimulant for depression, along with an ADHD medication. Wellbutrin (bupropion) and Effexor (venlafaxine) are the most frequently prescribed antidepressants prescribed "off-label" for ADHD. These drugs increase the levels of neurotransmitters dop
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