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Here we exfoliate the layered pigment CaCuSi4O10 (Egyptian Blue, E via baseball milling and facile tip sonication into NIR fluorescent nanosheets (EB-NS). How big is EB-NS are tailored to diameters less then 20 nm and heights down seriously to 1 nm. EB-NS fluoresce at 910 nm in addition to fluorescence intensity correlates using the number of Cu2+ ions. Moreover, EB-NS show no bleaching and high brightness compared with other NIR fluorophores. The usefulness of EB-NS is demonstrated by in-vi