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Purpose To present the problems and possibilities of diagnostic and treatment in a patient with resistant exudative-constrictive pericarditis. Methods The male patient 31 y. was admitted to the clinic due to exudative pericarditis and arthritis of the left knee joint. His medical history periodic febrile fever with a cough, episodes of syncope and atrial fibrillation, treatment with antibiotics and corticosteroids with a temporary effect. Results No data were received for systemic disease, hypothyroidism, tumors. With CT in both lungs,