https://www.selleckchem.com/pr....oducts/napabucasin.h
Chronic neutrophilic leukemia (CNL) is a rare bone marrow proliferative tumor and a heterogeneous disorder. In 2016, the World Health Organization included activating mutations in the gene as one of the diagnostic criteria, with T618I being the most common mutation. The disease is often accompanied by splenomegaly, but no developmental abnormalities and significant reticular fibrosis, and no Ph chromosome and fusion gene. So, it is difficult to diagnose at the first presentation in the absence of classical symptoms. Herein we descri
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