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Furthermore, meaningful biological pathways were enriched in association with each of the experimental factors during EA stimulation. Our analysis showed the robustness of WGCNA and revealed important genes within specific modules and pathways which might be activated in response to EA analgesia. The findings may help to clarify the underlying mechanisms of EA and provide references for future verification of this study. Neurodegenerative diseases, such as Alzheimer's disease, cause a great deal of suffering for both patients and carers.
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