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This article reviews isolation-by-distance models in population genetics and the use of these models in the modern problem of human difference. The article presents a historical and conceptual review of isolation-by-distance models and contemporary scientific critiques of BRCs, followed by examples of the use of isolation-by-distance models in studies of human genetic variation. To address the shortcomings in the scientific critique of race, the author proposes combining Du Boisian demography with Darwinian evolutionary biology. From a Du Boisian de